Neonates, children who are seen in the early stages of the disease, and those with an altered immune response may have normal laboratory study results and no fever or constitutional symptoms.

新生儿、处于疾病早期的儿童以及那些免疫反应发生改变的患者，其实验室检查结果可以正常，没有发热及全身症状。

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Bottom line is that INCY addresses only criteria, improvement in constitutional symptoms.

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